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SpinChem

Mass Transfer Revolutionized

Quick easy and reproducible heterogeneous reactions from lab to production

SpinChem provide technology solutions that reshape the way chemical process work is performed. We are trusted as business partners by being service-minded, adaptable and genuinely interested in transforming your workflow. Our goal is to surprise you with state of the art technology that changes your work to a simpler, quicker, more stable and less resource consuming process.

Dr. Emil A. Byström

Dr. Emil A. Byström
CEO, SpinChem

…this makes SpinChem one of the most exciting new tools for lab and kiloplant in many years!


R&D Team Leader, AstraZeneca

Clearly the washings and workup were very easy, as well as the catalyst storage, since I can just leave it in the bed without any loss due to transfers.

Andrea Pettenuzzo
Synthetic Organic Chemist - Biocatalysis, Almac

The SpinChem RBR has become an often used technology for heterogeneous catalysis at our research group.

Dr. Dennis Kaufhold
Personal Care and Nutrition, BASF, Germany

Results are quite amazing; significantly improved reaction rate, very easy recycling and bullet-proof stability of our enzyme.

Dr. Michiel van Vliet
R&D Manager, ChiralVision, The Netherlands

...the immobilized transaminase was better protected from mechanical forces in the SpinChem device

Prof. Dr. Uwe T. Bornscheurer
Greifswald University, Germany

The use of a special mixing device, SpinChem RBR, was beneficial, in terms of eliminating the mass-transfer limitations, it enabled a simpler collection and recycling of the catalyst and minimized the mechanical wear of the solid catalyst, thus possibly prolonging the catalyst lifetime.

Sebastian Leveneur
Maitre de conférences HDR INSA de Rouen, Ind. Eng. Chem. Res. 2018, 57, 11, 3876–3886

The RBR worked very well and the beads were, as expected, intact. I have run 3 reaction cycles and it's still perfect, very little activity lost (around 2%, compared to the usual "catalyst in the pot" way that gave maybe a 60% activity loss after just one reaction cycle).

Andrea Pettenuzzo
Synthetic Organic Chemist - Biocatalysis, Almac

The RBR has been great! It cuts the processing time on our 100L reactor by more than half.

Roberto Estrada
Process Engineer, USA

The results with the RBR have been extremely convincing; so much so that I recommended it warmly to other colleagues working in biocatalysis as well.

Dr. -Ing. André Delavault
Karlsruhe Institute of Technology (KIT)

…the SpinChem reactor effectively reduces catalyst damage.

Teng Ma, Weixi Kong, Yunting Liu, Hao Zhao, Yaping Ouyang, Jing Gao, Liya Zhou, Yanjun Jiang
Applied Biochemistry and Biotechnology, Volume 194 (2022), pp. 4999–5016

The design of the RBR reactor allows the catalyst to be separated from the reaction mixture without any losses and additional operations such as filtration, washing and drying, as is the case when a batch reactor is used.

Krzysztof Polaczek, Eliza Kaulina, Ralfs Pomilovskis, Anda Fridrihsone, Mikelis Kirpluks
Journal of Polymers and the Environment, Volume 30 (2022), pp. 4774–4786

The SpinChem® reactor is ideal to be used with cells immobilized in hydrogel beads as catalysts.

Silvia Donzella, Concetta Compagno, Francesco Molinari, Francesca Paradisi, and Martina Letizia
Reaction Chemistry and Engineering, 8(12) (2023), pp. 2963-2966.

It is our great pleasure to be using this incredibly innovative and advanced piece of equipment. The Rotating Bed Reactor (RBR) developed by SpinChem is an irreplaceable assist that serves as a complementary device to our unique PepTrap™ enzyme immobilization platform.

Nick Enslin
Chief Technology Officer, Immobazyme

…using immobilized enzymes in the SpinChem reactor can be conducted with operational ease and recycled multiple times while demonstrating improved stability; thus, this technology has become increasingly appealing to users in the biocatalytic field.

Teng Ma, Weixi Kong, Yunting Liu, Hao Zhao, Yaping Ouyang, Jing Gao, Liya Zhou, Yanjun Jiang
Applied Biochemistry and Biotechnology, Volume 194 (2022), pp. 4999–5016

Conducting the epoxidation reaction in the RBR reactor facilitated the separation process and provided the opportunity of reusing the catalyst.

Krzysztof Polaczek, Eliza Kaulina, Ralfs Pomilovskis, Anda Fridrihsone, Mikelis Kirpluks
Journal of Polymers and the Environment, Volume 30 (2022), pp. 4774–4786

"The rotating bed reactor is specifically designed to maintain constant exposure of the solid reactant to a steady flow of reaction fluid, thanks to its rotation, thus creating optimal reaction conditions."

Chng et al., Acta Polytechnica Hungarica, 2024
Department of Mechanical Engineering, National University of Singapore

"The use of SpinChem's RBR helped mitigate catalyst deactivation, a common hurdle in intensified processes."

Philipp Petermeier, Jan Philipp Bittner, Tobias Jonsson, Pablo Domínguez de María, Emil Byström & Selin Kara
Communications Chemistry Journal, 2024, 7(57), pp. 1-10.

Microscopic view of rod-shaped molecules in various colors (blue, purple, and red) interacting with and attaching to a white spherical structure against a light background, demonstrating molecular binding processes relevant to chemical reaction engineering.

Starting with Biocatalysis

Biocatalysis employs enzymes to accelerate chemical reactions. However, traditional methods often suffer from low efficiency, high costs, and limited adaptability. SpinChem's Rotating Bed Reactor (RBR) addresses these challenges by enhancing efficiency, reducing reaction times, and increasing yields. This versatile technology is suitable for various industries, including:

  • Pharmaceutical
  • Flavour and Fragrances
  • Food and Beverage

Spinchem rotating bed reactors used for Industrial liquid remediation

Industrial Liquid Remediation

The adsorption process is vital for managing environmental pollutants and industrial waste treatment. Reducing waste and raw material consumption is key for sustainability. Our technology addresses inefficiencies, offering a more effective, adaptable solution—ideal for industries needing high performance and selectivity in processes —such as:

  • Radioactive wastewater treatment
  • Environmental pollutant management
  • Industrial wastewater management

A conceptual design solution showcasing innovative approaches to biocatalysis and heterogeneous chemical processes with spinchem rotating bed reactors

Tailored reactor design for improved mass transfer

Whether you're focused on pharmaceutical processes, environmental remediation, or industrial manufacturing, we deliver solutions tailored to your exact specifications.

Improve your reactions and processes

Due to its smart design, the SpinChem® RBR not only helps to transform fluids at a molecule level, but also addresses operational inefficiencies and environmental challenges.

Rotating bed reactor S2 with a grey background Rotating bed reactor S2 with a grey background Rotating bed reactor S2 with a grey background

  • Short reaction time

    Due to faster mass transfer

  • Long catalyst lifetime

    Due to protected solid phase

  • No filtration required

    Due to the product design

Facing mass transfer challenges?

See how innovative SpinChem RBR technology can transform your chemical processes by enhancing reaction efficiency, minimizing operational expenses, and providing seamless scalability from laboratory to industrial production

Simple to scale

The SpinChem® RBR enables consistent and predictable results from laboratory to pilot stage and production with solutions possible for processing liquids from 150 ml up to thousands of cubic meters.

Diverse solid-liquid processes

RBR technology accommodates various heterogeneous reactions with diverse solid phases. Its flexible design allows for seamless integration into existing production lines and processes.

Cost-efficient

The enhanced mass transfer efficiency leads to higher product yields and better product quality, while reducing operational costs, making it an attractive investment for industries.

Scaling reactions from the lab to a factory

SpinChem® RBR S2 Starter Kit, a complete setup for optimizing biocatalysis, adsorption, and other chemical processes in laboratory-scale applications.

Lab scale starter kits

This is typically where you would start in most cases. Begin with initial screening and development of your process…

SpinChem® ATEX-certified rotating bed reactor (RBR), designed for safe chemical processes in explosive environments, ensuring efficient biocatalysis and adsorption applications.

Production scale deployment

Universal solutions for diverse challenges, from wastewater treatment to the synthesis of active pharmaceutical ingredients…

Committed to excellence

We've earned the trust of clients across academia, research, and diverse industries.

Meet SpinChem's valued partners who have chosen rotating bed reactor technology

SpinChem collaborations with research institutions and industries

Transform your chemical processing with industry-leading solutions

We partner with leading academic institutions to develop cutting-edge technologies that maximize efficiency, reduce operational costs, and deliver superior ROI for your chemical processing needs. Invest in proven solutions trusted by global industry leaders.

countries where we have customers

Become a distributor?

scientific publications featuring RBR technology

Scientific Literature

Largest pharmaceutical companies are our customers

Customers' stories

SpinChem Events

SpinChem team member presenting innovative biocatalysis solutions at a conference with rotating bed reactor displayed at the banner

Biotrans 2025

Meet SpinChem at International Symposium on Biocatalysis and Biotransformations

29 Jun 2025 - 03 Jul 2025

Basel, Switzerland

09:00 - 09:00

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Wondering if RBR technology suits your application?

Our team of specialists is ready to help with your questions and provide solutions to your mass transfer challenges. Contact us today