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SpinChem

Leading Technology for Superior Mass Transfer

Reliable scale-up from lab to production

Trusted by leading innovators in pharma, nuclear, cleantech worldwide

SpinChem provide technology solutions that reshape the way chemical process work is performed. We are trusted as business partners by being service-minded, adaptable and genuinely interested in transforming your workflow. Our goal is to surprise you with state of the art technology that changes your work to a simpler, quicker, more stable and less resource consuming process.

Dr. Emil A. Byström

Dr. Emil A. Byström
CEO, SpinChem

…this makes SpinChem one of the most exciting new tools for lab and kiloplant in many years!


R&D Team Leader, AstraZeneca

Clearly the washings and workup were very easy, as well as the catalyst storage, since I can just leave it in the bed without any loss due to transfers.

Andrea Pettenuzzo
Synthetic Organic Chemist - Biocatalysis, Almac

The SpinChem RBR has become an often used technology for heterogeneous catalysis at our research group.

Dr. Dennis Kaufhold
Personal Care and Nutrition, BASF, Germany

Results are quite amazing; significantly improved reaction rate, very easy recycling and bullet-proof stability of our enzyme.

Dr. Michiel van Vliet
R&D Manager, ChiralVision, The Netherlands

...the immobilized transaminase was better protected from mechanical forces in the SpinChem device

Prof. Dr. Uwe T. Bornscheurer
Greifswald University, Germany

The use of a special mixing device, SpinChem RBR, was beneficial, in terms of eliminating the mass-transfer limitations, it enabled a simpler collection and recycling of the catalyst and minimized the mechanical wear of the solid catalyst, thus possibly prolonging the catalyst lifetime.

Sebastian Leveneur
Maitre de conférences HDR INSA de Rouen, Ind. Eng. Chem. Res. 2018, 57, 11, pp.3876–3886

The RBR worked very well and the beads were, as expected, intact. I have run 3 reaction cycles and it's still perfect, very little activity lost (around 2%, compared to the usual "catalyst in the pot" way that gave maybe a 60% activity loss after just one reaction cycle).

Andrea Pettenuzzo
Synthetic Organic Chemist - Biocatalysis, Almac

The RBR has been great! It cuts the processing time on our 100L reactor by more than half.

Roberto Estrada
Process Engineer, USA

The results with the RBR have been extremely convincing; so much so that I recommended it warmly to other colleagues working in biocatalysis as well.

Dr. -Ing. André Delavault
Karlsruhe Institute of Technology (KIT)

…the SpinChem reactor effectively reduces catalyst damage.

Teng Ma, Weixi Kong, Yunting Liu, Hao Zhao, Yaping Ouyang, Jing Gao, Liya Zhou, Yanjun Jiang
Applied Biochemistry and Biotechnology, Volume 194 (2022), pp.4999–5016

The design of the RBR reactor allows the catalyst to be separated from the reaction mixture without any losses and additional operations such as filtration, washing and drying, as is the case when a batch reactor is used.

Krzysztof Polaczek, Eliza Kaulina, Ralfs Pomilovskis, Anda Fridrihsone, Mikelis Kirpluks
Journal of Polymers and the Environment, Volume 30 (2022), pp.4774–4786

The SpinChem® reactor is ideal to be used with cells immobilized in hydrogel beads as catalysts.

Silvia Donzella, Concetta Compagno, Francesco Molinari, Francesca Paradisi, and Martina Letizia
Reaction Chemistry and Engineering, 8(12) (2023), pp.2963-2966.

It is our great pleasure to be using this incredibly innovative and advanced piece of equipment. The Rotating Bed Reactor (RBR) developed by SpinChem is an irreplaceable assist that serves as a complementary device to our unique PepTrap™ enzyme immobilization platform.

Nick Enslin
Chief Technology Officer, Immobazyme

…using immobilized enzymes in the SpinChem reactor can be conducted with operational ease and recycled multiple times while demonstrating improved stability; thus, this technology has become increasingly appealing to users in the biocatalytic field.

Teng Ma, Weixi Kong, Yunting Liu, Hao Zhao, Yaping Ouyang, Jing Gao, Liya Zhou, Yanjun Jiang
Applied Biochemistry and Biotechnology, Volume 194 (2022), pp.4999–5016

Conducting the epoxidation reaction in the RBR reactor facilitated the separation process and provided the opportunity of reusing the catalyst.

Krzysztof Polaczek, Eliza Kaulina, Ralfs Pomilovskis, Anda Fridrihsone, Mikelis Kirpluks
Journal of Polymers and the Environment, Volume 30 (2022), pp.4774–4786

"The rotating bed reactor is specifically designed to maintain constant exposure of the solid reactant to a steady flow of reaction fluid, thanks to its rotation, thus creating optimal reaction conditions."

Chng et al., Acta Polytechnica Hungarica, 2024
Department of Mechanical Engineering, National University of Singapore

"The use of SpinChem's RBR helped mitigate catalyst deactivation, a common hurdle in intensified processes."

Philipp Petermeier, Jan Philipp Bittner, Tobias Jonsson, Pablo Domínguez de María, Emil Byström & Selin Kara
Communications Chemistry Journal, 2024, 7(57), pp.1-10.

Microscopic view of rod-shaped molecules in various colors (blue, purple, and red) interacting with and attaching to a white spherical structure against a light background, demonstrating molecular binding processes relevant to chemical reaction engineering.

Starting with Biocatalysis

Biocatalysis employs enzymes to accelerate chemical reactions. However, traditional methods often suffer from low efficiency, high costs, and limited adaptability. SpinChem's Rotating Bed Reactor (RBR) addresses these challenges by enhancing efficiency, reducing reaction times, and increasing yields. This versatile technology is suitable for various industries, including:

  • Pharmaceutical
  • Flavour and Fragrances
  • Food and Beverage

Spinchem rotating bed reactors used for Industrial liquid remediation

Industrial Liquid Remediation

The adsorption process is vital for managing environmental pollutants and industrial waste treatment. Reducing waste and raw material consumption is key for sustainability. Our technology addresses inefficiencies, offering a more effective, adaptable solution—ideal for industries needing high performance and selectivity in processes —such as:

  • Radioactive wastewater treatment
  • Environmental pollutant management
  • Industrial wastewater management

Popular products

SpinChem Essentials Kit Minirbr consisting of a lab tube and a miniature reactor

SpinChem® Essentials kit MiniRBR

SKU: #9014-00285 Miniature rotating bed reactor kit containing 1 MiniRBR and 1 tube vessel or fast, reproducible screening of catalysts, enzymes, and other solid phases. Note: Table rack and stirrer kit are not included. Price: €99

SpinChem Rotating bed reactor s2 used for optimizing mass transfer in chemical processes

SpinChem® RBR S2

SKU: 1221-001 The SpinChem® RBR S2 is an innovative technology designed for efficient and scalable heterogeneous reactions in laboratory settings. Engineered for use in vessels ranging from 100 to 500 mL, this reactor enhances mass transfer processes, making it ideal for applications in biocatalysis, chemical synthesis, and environmental engineering. €3,717 (excluding accessories such as shaft, filters, and assembly tools)

SpinChem® RBR S2 Starter Kit, a complete setup for optimizing biocatalysis, adsorption, and other chemical processes in laboratory-scale applications.

Complete Starter Kit S2

SKU: 9200-001 The Complete starter kit S2 is the optimal system to start developing your process. Often used for screening reaction conditions and exploring the application at an early stage, the Complete starter kit S2 offers a streamlined workflow and simplifies the daily operations in the laboratory. Suitable for 120-300 mL liquid volume. €8,001

A conceptual design solution showcasing innovative approaches to biocatalysis and heterogeneous chemical processes with spinchem rotating bed reactors

Scale up with confidence

Our process development services guide you from feasibility to full-scale production across pharmaceutical, environmental, and industrial applications, mitigating scale-up risks at every step.

Improve your reactions and processes

Due to its smart design, the SpinChem® RBR not only helps to transform fluids at a molecule level, but also addresses operational inefficiencies and environmental challenges.

Rotating bed reactor S2 with a grey background Rotating bed reactor S2 with a grey background Rotating bed reactor S2 with a grey background

  • Short reaction time

    Due to faster mass transfer

  • Long catalyst lifetime

    Due to protected solid phase

  • No filtration required

    Due to the product design

Facing mass transfer challenges?

See how innovative SpinChem RBR technology can transform your chemical processes by enhancing reaction efficiency, minimizing operational expenses, and providing seamless scalability from laboratory to industrial production

Simple to scale

The SpinChem® RBR enables consistent and predictable results from laboratory to pilot stage and production with solutions possible for processing liquids from 150 ml up to thousands of cubic meters.

Diverse solid-liquid processes

RBR technology accommodates various heterogeneous reactions with diverse solid phases. Its flexible design allows for seamless integration into existing production lines and processes.

Cost-efficient

The enhanced mass transfer efficiency leads to higher product yields and better product quality, while reducing operational costs, making it an attractive investment for industries.

Scaling reactions from the lab to a factory

SpinChem® RBR S2 Starter Kit, a complete setup for optimizing biocatalysis, adsorption, and other chemical processes in laboratory-scale applications.

Lab scale starter kits

This is typically where you would start in most cases. Begin with initial screening and development of your process…

SpinChem® ATEX-certified rotating bed reactor (RBR), designed for safe chemical processes in explosive environments, ensuring efficient biocatalysis and adsorption applications.

Production scale deployment

Universal solutions for diverse challenges, from wastewater treatment to the synthesis of active pharmaceutical ingredients…

SpinChem collaborations with research institutions and industries

Transform your chemical processing with industry-leading solutions

We partner with universities and research institutions worldwide to develop new processes and applications using rotating bed reactor technology, helping customers improve efficiency, reduce costs, and simplify scale-up.

countries where we have customers

See our local partners

scientific publications featuring RBR technology

Scientific literature

largest pharmaceutical companies are our customers

Customers' stories

SpinChem Events

Smart Labtech (India) x SpinChem: Removing Bottlenecks in Solid-Liquid Processing

02 Jun 2026

Online

12:30 - 13:00

Biocat 2026

Meet SpinChem at Biocat 2026, the 12th International Congress on Biocatalysis, where the global biocatalysis community meets to share advances in enzyme catalysis and industrial bioprocess development. SpinChem will participate as part of the Enzyme Technology Alliance (ETA), a collaboration that brings complementary expertise across the journey from enzyme discovery and engineering to immobilization and scalable process implementation. Learn more about the Enzyme Technology Alliance We will be available to discuss how rotating bed reactor (RBR) technology supports scalable, reproducible biocatalysisby improving mass transfer while keeping solids protected and contained. Practical approaches to enzyme immobilization and multi-cycle reuse Catalyst compartmentalization for multi-step or incompatible catalyst setups Scale-up pathways from lab to production with consistent processing logic Event details Dates: August 23–27, 2026 Location: Hamburg University of Technology (TUHH), Hamburg, Germany Official event page: https://biocat-congress.de/ Meet SpinChem Interested in exploring how RBR technology could support your biocatalysis route or scale-up plans? Contact us to schedule a meeting in Hamburg.

23 Aug 2026 - 27 Aug 2026

Hamburg, Germany

12:00 - 12:00

OxiZymes 2026 Bochum

Meet SpinChem at OxiZymes 2026, the 12th edition of the OxiZymes conference series covering Enzyme Mining and Engineering Enzymology and Biochemistry Biotechnology and Applications You can meet SpinChem at the conference to discuss and discuss how rotating bed reactor (RBR) systems can support biocatalysis processes by improving gas–liquid–solid mass transfer, enabling catalyst compartmentalization, and simplifying reuse of immobilized enzymes. Event details Dates: September 29 – October 2, 2026 Location: Ruhr-Universität Bochum, Bochum, Germany Official event page here If you are attending OxiZymes 2026 and want to discuss enzyme immobilization, scale-up logic, or practical evaluation setups, contact us to arrange a meeting in Bochum.

29 Sep 2026 - 02 Oct 2026

Ruhr-Universität Bochum

12:00 - 12:00

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Wondering if RBR technology suits your application?

Our team of specialists is ready to help with your questions and provide solutions to your mass transfer challenges. Contact us today