A comprehensive review of biocatalysis covering how the recent advances in engineering of enzymes, substrates, media and reactor design contribute to a sustainable chemistry development. The authors wrote that SpinChem® RBR technology “combines the advantages of a stirred tank with those of a packed bed” thus giving benefits by “circumventing mechanical attrition of the biocatalyst” while “mass transfer is greatly accelerated”.
Role of biocatalysis in sustainable chemistry
Roger A. Sheldon and John M. Woodley
Chem. Rev., 2018, 118(2), pp. 801-838.